This component involves the use of LC-MS/MS (Liquid Chromatography-Mass Spectrometry/Mass Spectrometry) to analyze drug levels in various matrices. It also includes method development and extraction techniques like precipitation, liquid-liquid extraction (LLE), and solid-phase extraction (SPE) for sample preparation. Overall, these DMPK services cover a wide range of critical assessments and analyses that are essential for understanding the pharmacokinetics, safety, and efficacy of drug candidates, ultimately helping in the development of safe and effective pharmaceuticals.

LC-MS/MS-Based Bioanalysis: Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS) is a powerful analytical technique used to quantify the concentration of drugs and their metabolites in various biological samples. It provides high sensitivity and specificity, making it the method of choice for bioanalysis in drug development./p>