In Vitro Mammalian Chromosomal Aberration (OECD 473, ICH S2R1 ) study examines whether a compound can cause structural abnormalities in the chromosomes of mammalian cells grown in culture, a significant indicator of genotoxicity.

In Vitro Mammalian Chromosomal Aberration test evaluates the compound's potential to induce chromosomal damage in cultured mammalian cells.